Joint Flex Triva
Joint Flex Triva

KKLIU 1337/2017

PROMOTE JOINT COMFORT AS EARLY AS 7 DAYS


Arthritis is a common condition that causes pain, inflammation and stiffness in and around one or more of your joints. Osteoarthritis, also known as “wear and tear” arthritis is characterized by progressive degeneration of the cartilage of the joints, occurring mainly in older people. It is also more likely to occur in people who are overweight or obese and in those with jobs that stress particular joints. The condition most frequently affects the joints of knees, hips, hands, lower back and neck. 

A typical modern diet that is excessive in omega-6 fatty acids and deficient in omega-3 fatty acids leads to chronic inflammation in your body. Elevated production of arachidonic acid (AA) in the body, as a result of consumption of foods high in omega-6 fatty acids such as red meats, dairy products, eggs and refined oils has shifted the balance of fatty acid metabolism toward an increase in pro-inflammatory metabolite generation, via the LOX (5-lipoxygenase) and COX (cyclooxygenase) enzymatic pathways, causing inflammation, distorted joints and tissue destruction.

NSAIDs are frequently used to inhibit the COX route to relieve the joint pain. However, it induces gastric side effects as COX-1 is responsible for maintenance and protection of the gastrointestinal tract. There are new generation NSAIDs that selectively block only the COX-2 pathway but still allow the production of leukotrienes through the 5-LOX inflammation pathway, which cause devastating effects on joints, arterial walls and other tissues.


OLIFERIN® JOINT FLEX TRIVA contains olive phytonutrients, especially hydroxytyrosol, AKBA (boswellia serrata extract), curcuminoids (turmeric extract) and nutrient enhancer Bioperine® black pepper extract, to offer fast and natural pain relief and support joint and muscular health.



Boswellia Serrata – The Ancient Herb For Joints

Boswellia serrata is a tree producing a highly scented sap that has been prized for its healing properties since ancient times. It preserves healthy muscle & joint mobility, supports normal inflammation processes and helps maintain healthy connective tissues.Of the active compounds in the Boswellia extract, Acetyl-11-keto-ß-boswellic acid (AKBA) has been identified as the most powerful, demonstrating pronounced inhibitory against 5-LOX.


Apresflex® – Fast Acting 5-Lox Inhibitor

ApresFlex® is a clinically tested gum resin extract of boswellia serrata enriched with at least 20% AKBA and its non-volatile oil. Clinical data showed that compared to AKBA alone, the synergism with the non-volatile oil promotes faster absorption, quick and long lasting therapeutic benefits, making it a potent anti-inflammatory agent.  Moreover, this novel Boswellia extract significantly inhibits matrix metalloproteinase (MMP-3), enzymes that break down cartilage, collagen and connective tissues.

 

CLINICAL STUDY

A 90-day, double blind, randomized, placebo-controlled study was conducted to evaluate the efficacy and tolerability of ApresFlex®in the treatment of Osteoarthritis (OA) of the knee. Sixty OA subjected were enrolled in the study and each patient was evaluated for pain and physical functions. The observations suggested  that 100mg ApresFlex® (2 capsules of OLIFERIN JOINT FLEX TRIVA) conferred clinically and statistically improvements (P<0.0001) in pain score and physical function scores in OA subjects within 7 days.

  

The rhizome of turmeric (Curcuma longa L.) has a rich history in India as a spice, food preservative and coloring agent and has been used for centuries in the Ayurvedic system of medicine. Turmeric extract derived curcuminoids  (the main component curcumin, demethoxycurcumin and bisdemethoxycurcumin) offer antioxidant  and anti-inflammatory support, promote healthy immune function, and potentially prevent connective tissue break down through inhibiting destructive enzymes, with benefits in healthy aging (Aggarwal B. et al.(2006). Turmeric: The Genus Curcuma. pp 297-368).


Bioperine® is a standardized extract from the fruits of Piper nigrum L. (black pepper) and contains a minimum piperine content of 95% compared to the 3-9% found in raw form. It is said that when piperine is ingested, it has a localized thermogenic effect on epithelial cells which increase the uptake of nutrients.

 

Indication:
Traditionally used for relief of joint and muscular pain.

Recommended Dosage:
Take 2 capsules each time, 1 time daily after a meal.

Active Ingredients:
Fructus Olea europaea extract 50mg, ApresFlex® Resina Boswellia serrata extract 50mg, Rhizoma Curcuma Longa Extract 100mg and Fructus Piper Nigrum Extract 2mg

 

*This is a traditional medicine. If symptoms persist, please consult a doctor.*