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Celiac Disease (CD)
(0) Celiac Disease (CD)
Celiac Disease (CD) is an autoimmune disease characterized by inflammation of the intestinal mucosa due to an immune response to wheat gliadins.
Myalgia
(0) Myalgia
Myalgia is the medical term for muscle pain. Myalgia are extremely common. Almost everyone has experienced discomfort in their muscles at some point. Because there’s muscle tissue in nearly all parts of the body, this type of pain can be felt practically anywhere. However, there’s no single cause for muscle aches and pains. Acute (short-term) causes of myalgia include muscle strains or overuse, infections, and vitamin deficiencies. Chronic (long-term) conditions can also cause muscle pain and soreness. These include fibromyalgia, rheumatoid arthritis, and depression. Depending on the underlying condition, myalgia treatment may involve medication, self-treatment, and physical therapy.
The essential nutrient – CoQ10
(0) The essential nutrient – CoQ10

By Nutritionist Avril

 

Coenzyme Q-10 (CoQ-10 or Ubiquinone) is a quinone that occurs naturally in most aerobic organisms. It was discovered in 1940 and isolated in 1957 from the mitochondria of beef heart. Coenzyme Q, CoQ, CoQ10, Ubiquinone, Ubiquinone-Q10, Ubidecarenone, and Vitamin Q10 are all names for Coenzyme Q. CoQ10, which has 10 isoprene repetitions, is the most prevalent form of CoQ. CoQ10 is present in human tissues, with the largest concentrations found in organs with high metabolic rates, such as the heart, kidney, and liver. 

 

Coenzyme Q-10 acts as an energy transfer molecule in the electron-transport chain, which is responsible for the synthesis of adenosine triphosphate (ATP). Because ATP is required for most cellular processes, CoQ10 is vital for the health of all human tissues and organs. It also functions as a lipid antioxidant, limiting free radical formation and preserving proteins, lipids, and DNA. 

 

The concentration of CoQ10 declines in illness situations associated with increased reactive oxygen species (ROS), leading to respiratory chain malfunction and impaired cell efficiency. To neutralise free radicals, humans have evolved a sophisticated antioxidant defence system that includes CoQ10 and other antioxidants obtained from nutrition, antioxidant enzymes, metal-binding proteins, and antioxidant phytonutrients present in plant meals. 

 

CoQ10 supplements may have potential benefits in preventing or treating a variety of conditions, including cardiovascular disease, high blood pressure, cancer, periodontal diseases, mitochondrial disorders, radiation injury, obesity, diabetes, Parkinson's disease, AIDS, gastric ulcers, allergy, migraine headaches, kidney failure, muscular dystrophy, and ageing. CoQ10 is essential for improving the immune system and physical performance. It is derived mostly from dietary sources such as oily fish, organ meats, and whole grains. Supplementation, on the other hand, may be required for those with certain health issues.

 

CoQ10 is available in a variety of forms, with daily doses ranging from 30 to 200 mg. It is more easily absorbed when combined with an oil or fat-containing meal. The therapeutic results may take up to eight weeks to manifest, and side effects such as diarrhoea and dermatitis are possible. CoQ10 level in the body diminishes with age, and it is present in cell membranes, particularly mitochondrial membranes, in numerous organs. 

 

To summarise, Coenzyme Q10 is a critical component in the body that is involved in energy generation and antioxidant defence, with potential advantages for a variety of health concerns.

 

References:

1. Battino M, Ferreiro MS, Bomparde S, Leone L, Mosca F, Bullon P. Elevated hydroperoxide levels and antioxidant patterns in Papillon-Lefevre syndrome. J Periodontol. 2001;72:1760–6. 

2. Battino M, Bullon P, Wilson M, Newman N. Oxidative injury and inflammatory periodontal diseases: The challenge of antioxidants to free radicals and reactive oxygen species. Crit Rev Oral Biol Med. 1999;10:458–76. 

3. Saini R, Saini S, Sharma S. Antioxidants accelerates cellular health. Int J Green Pharm. 2010;3:212. 

 

Tuberculosis
(0) Tuberculosis
Tuberculosis (TB) is an infectious disease caused by the bacteria called Mycobacterium tuberculosis. Mycobacterium tuberculosis is a rod-shaped,nonmotile, acid-fast bacterium. Tuberculosis affects mainly the lungs (Pulmonary Tuberculosis), but it can infect other organs of the body like bones, joints, genito-urinary, intestines, skin, tuberculous meningitis and others.
CONSUMPTION OF FISH AND SHELLFISH – ARE THEY FREE FROM TOXICITY?
(0) CONSUMPTION OF FISH AND SHELLFISH – ARE THEY FREE FROM TOXICITY?
Fish is among the choice people seek for their consumption instead of poultry and meat. They belong to protein class which is very important for muscle growth and other body functions. If people have protein deficiency, it will lead to stunted, decrease muscle mass, low immunity, weakening of heart and respiratory system (Harvard T.H. Chan, 2023). Salmon, tuna, mackerel, sea bass, trout, anchovy and others (UNESCO, 2023) are the famous choice we consume in the world wide. However, there might be a concern about the safety on consumption of fish or sea products including the level of toxicity caused by heavy metal, radiation and other pollution.
Are you eating too much sugar?
(0) Are you eating too much sugar?
The 2019 National Health and Morbidity Survey (NHMS) estimated that 18% of the total population has diabetes, while nearly 50% of the total population is overweight or obese. It is also estimated that Malaysian consume on average 12 teaspoons of sugar per day from sugar-sweetened beverages. The overconsumption of sugar is one of the key contributing factors to obesity and development of non-communicable diseases (NCDs).
Dehydration vs heat stroke
(0) Dehydration vs heat stroke
During extremely hot weather, it is easy for our body to overheat and thus become dehydrated. This can lead to life-threatening heat-related illness such as heat stroke and heat exhaustion. Heat can also make existing illnesses worse (for example may trigger a heart attack in someone with a heart condition), cause serious permanent injuries (such as damage to the brain or other vital organs), and in extreme cases result in death.
Heat wave
(0) Heat wave
A heat wave, or heatwave, or extreme heat, is a period of excessively hot weather, which may be accompanied by high humidity. While definitions vary, a heat wave is usually measured relative to the usual climate in the area and relative to normal temperatures for the season. Temperatures that people from a hotter climate consider normal can be called a heat wave in a cooler area if they are outside the normal climate pattern for that area. Heat waves, which can last for several days, can have a significant impact on society, including a rise in heat-related deaths. Heatwaves are among the most dangerous of natural hazards, but rarely receive adequate attention because their death tolls and destruction are not always immediately obvious. Population exposure to heat is increasing due to climate change. Globally, extreme temperature events are observed to be increasing in their frequency, duration, and magnitude. Between 2000 and 2016, the number of people exposed to heatwaves increased by around 125 million.
POWER SUPPLY FOR HEART AND ATHLETES
(0) POWER SUPPLY FOR HEART AND ATHLETES
CoQ10 level may be reduced during times of intense training due to metabolic stress and elevation of free radical formation for most athletes. Therefore, the supplementations of CoQ10 will help in aerobic power, anaerobic threshold, exercise performance, and/or recovery after exercise in trained athletes and untrained individuals, and increase muscle CoQ10 concentration with 100-200 mg/day. Supplementation below this dosage may not give any effects on exercise performance as described in many studies.
Common supplements for Joint Pain
(3035) Common supplements for Joint Pain
Knee pain is often underreported, underestimated and under treated. The estimated prevalence of knee pain among individuals aged 55 years and older residing in Kuala Lumpur, Malaysia was 30.8%, while the prevalence of self-reported OA symptoms over the past year was 25.4%. Pain relievers such as paracetamol (Panadol) or NSAIDs such as ibuprofen (Nurofen), are usually the first choice for joint pain relief. There are also a lot of supplements that claim to work for treating joint pain, but which ones actually work?